Our most popular pain relieving gel. Biofreeze Pain Relieving Gel is indicated for: Back and muscle pain, Arthritis pain, Shoulder and neck pain, Sports Injury Pain, Painful Joint, and Tendonitis/Bursitis. Biofreeze is effective in relieving pain because it contains an herb called ILEX. Biofreeze creates a cooling sensation within the skin and penetrates deep, for a longer lasting pain relief than conventional gels. Biofreeze with ILEX is greaseless, stainless and has no lingering odor. Biofreeze is sold by doctors across the country for their patients with pain. Try it today.